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Samples were centrifuged at 5000 g for 30 seconds, and bead pellets washed 3 in 500 L wash buffer (50 mM Tris-HCl, 150 mM NaCl, pH 7.4) before storage at 80 C until further analysis

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Moving beyond inflammation as a therapeutic target for crohn's disease

GLP-1 immunoreactive fibers and nerve terminals are distributed in the parvocellular parts of the PVN and innervate this structure, directly connecting GLP-1 with the CRH neurons [72]

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In addition to Wegovy and Ozempic, the GLP-1 class includes Eli Lilly's highly popular weight loss drug Zepbound and diabetes treatment Mounjaro