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Research suggests that oxidative stress may play a role in inflammatory skin concerns, including acne

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Furthermore, randomized controlled trials have shown that thyroidectomy can improve quality of life and reduce antibody levels in selected patients with persistent symptoms despite adequate levothyroxine therapy

If you do have decreased kidney function and your doctor recommends methylcobalamin, you may need a much higher dose because its less stable, so be sure to ask them about whats best given your condition