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It requires sterile technique, causes discomfort for needle-averse individuals, creates potential injection site reactions, and demands careful rotation to avoid tissue damage over extended protocols

(ref) Chang CH, Tsai WC, Hsu YH, Pang JH

10.1016/j.ecoenv.2018.06.070 25 GuderleyH.LapointeD.BdardM.DutilJ

Hepatology 77 (1), 7791

You have signs of dehydration (such as dizziness or very dark urine) Your appetite or weight suddenly or unusually changes You have some symptoms related to diabetes, such as very high or low blood sugar Its better to check early if you think that theres something that doesnt feel right

The soft tissue over the lower back and hip has a generous fat pad and tends to be less sensitive