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A.OkajimaS

J Clin Invest (2020) 130(9):501126

Table 1 Echocardiographic and hemodynamic (pressure-volume loop) assessment

Hormonal Regulation : Hormones like insulin can enhance the expression of enzymes involved in carnitine biosynthesis, adjusting the pathways activity in response to metabolic states

Conclusion Numbness and tingling can occur while you're taking Ozempic, but the medication is not clearly established as a common direct cause

The important caveat here is that there were very few events overall in the study 15 on drug treatment vs 32 on placebo so we need to treat this more directionally