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To evaluate the efficacy of melatonin across these age groups, cumulus cells were isolated from patients and subjected to gene expression analysis for cuproptosis-related genes (ATP7B, SLC31A1, FDX1, DLD, DLAT) and ferroptosis-related genes (TFRC, GPX4, NCOA4, SLC3A2, SLC7A11)

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About 20% of patients taking the higher dose in both trials experienced this effect, compared with about 5% of those on the lower dose

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Wegovy typically leads to more weight loss due to higher dosing than Ozempic