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The primary endpoint of the study is the time to the first occurrence of cardiovascular death, non fatal myocardial infarction (MI), non fatal stroke, or heart failure (HF) within 5 years of treatment

CARS2 is originally known as a mitochondrial isoform of cysteinyl t-RNA synthetase, and the persulfide synthesizing activity is a moon-lighting function of CARS2

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Do not proceed with it

In rare cases, people do go to the hospital

Additionally, we discovered that a GSH threshold of 10.2 nmol/mg effectively differentiates resistant cells from sensitive cells, with an AUC of 0.913, providing a robust distinction between chemotherapy-resistant and sensitive patients