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The roles of glutathione peroxidases during embryo development

PLoS ONE 6 , e17706e17706 (2011)

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The primary objective was to collect long-term safety data on the use of mecasermin for the treatment of children with growth failure

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We also used cell-permeable 2-OG (dimethyl 2-OG, DM-2OG), as a control for 2-OG accumulation driving 2-HG formation, as excess 2-OG has been previously shown to drive PHD inhibition via L-2-HG 22,24