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The appetite decrease is of course part of the intended mechanism, but it can become excessive during aggressive titration, leading to inadequate caloric and protein intake

Where GLP-1 primarily activates hypothalamic neurons involved in energy balance, amylin targets hindbrain circuits that regulate meal-specific satiety and food reward

Additionally, it aids in preventing and treating some forms of lung cancer

Dingxi Liu, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers