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Additional research will help clarify whether these reactions are direct drug effects or secondary immune responses

In that trial, 4,286 (24.3%) of patients had heart failure with 1,347 of those patients having heart failure with reduced ejection fraction dwarfing the small numbers studied in the initial trials mentioned previously

Liraglutide (Saxenda/Victoza)

A large phase 3 trial with hard endpoints and long follow-up is a far stronger basis for clinical decisions than a phase 2 signal, however impressive that signal is

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Retatrutide's 24.2% came at 48 weeks