Youre losing fat aka your natural insulation These medications often lead to weight loss, and as that subcutaneous fat melts away, so does the warm, cozy buffer that used to keep you from feeling like a popsicle
Trends in first-time prescribing First-time prescribing rates (first-time GLP-1 RA prescriptions per total prescriptions) increased 12.02% in March 2025 compared to December 2024
Nagamani SCS, Campeau PM, Shchelochkov OA, Premkumar MH, Guse K, Brunetti-Pierri N, et al
Supplementation with GSH rescues cancer cell survival and growth in cystine-deficient conditions, and this rescue depends on the catabolic activity of -glutamyltransferases
Tirzepatide, marketed under the brand name Zepbound, is a dual agonist that targets the glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptors
11 Impact on PharmD/CDCES: Pharmacists/CDCES can help identify patients that would most benefit from tirzepatides A1c lowering and weight reducing effects Pharmacists/CDCES can provide appropriate patient counseling regarding tirzepatides administration, benefits, adverse drug reactions, and storage Pharmacists/CDCES can assist other healthcare providers to safely transition patients from a GLP-1 RA to tirzepatide Pharmacists can facilitate insurance/cost barriers for eligible patients based on approved indications References: Type 2 diabetes treatment to lower A1C: Mounjaro(tirzepatide).Mounjaro
