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Phase 2 clinical data showed that starting at lower doses (1-2mg) partially mitigated gastrointestinal side effects compared to more aggressive starting doses

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[DOI] [PMC free article] [PubMed] [Google Scholar] 62.Yammine L, Green CE, Kosten TR, de Dios C, Suchting R, Lane SD, et al

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When to contact your provider Do not wait for your scheduled check-in if you experience: Severe or persistent nausea that prevents eating or drinking Signs of dehydration (dark urine, dizziness, dry mouth) Severe abdominal pain Unusual swelling in your legs or feet Signs of an allergic reaction No appetite suppression at all after several weeks If your Belle Health provider is not responsive, as some reviewers have noted, be persistent