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A logical target whereby metformin could mediate its putative antiproliferative effects in cancer is via inhibition of mTOR and the serine-threonine kinase, ribosomal S6K (pS6K), either via activation of AMPK or via an AMPK-independent pathway (241, 242)
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The same is true for those who lose weight by dietingafter the diet ends, they typically regain the weight
Mild skin irritation, redness, or tingling at the application site
Disponibile all'indirizzo: Xie, J., et al
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