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Statistics Statistical analyses were preplanned in a statistical report and analysis plan prior to database closure

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Drink more water

Losing 25 pounds or more can sometimes reveal hollowing through the cheeks, flattening of the midface, temple deflation, or subtle sagging along the lower face

As inflammation recedes, blood vessels regain their natural flexibility, helping blood flow more smoothly and easily and allowing blood pressure to drop

A phase II trial focusing on individuals with overweight or obesity, coupled with hypertension or dyslipidemia but without T2D, found that cagrilintide (2.4 mg) alongside diet and exercise, led to a 10% body weight reduction compared to 3% with placebo over 26 weeks [99]