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EMS can severely disrupt the cell cycle of follicular granulosa cells and increase the apoptotic rate of granulosa cells in patients ( in vitro fertilization ( The targets of differentially expressed CircRNAs were predominantly connected to apoptosis, Phosphatidylinositol3-kinase-RAC-beta serine/threonine-protein kinase(PI3K-AKT), and Cellular tumor antigen p53 signaling pathways by sequencing the CGCs of women with EMS and women without EMS ( 4.2 EMS promotes inflammation and oxidative stress in GCs Inflammation and oxidative stress can impair oocyte quality and potentially cause follicular atresia

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