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This will be administered subcutaneously

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Drug Interactions: Omeprazole Injection may interact with certain medications, including digoxin, warfarin, and ketoconazole

As one expert says, Regular monitoring is essential to tailor Vitamin B12 therapy to individual patient needs and prevent over- or under-treatment. Response-Based Dosing Strategies We adjust Vitamin B12 doses based on how well the patient responds

This suggests a very good safety and tolerability profile indistinguishable from placebo in those trial settings