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Key Findings: Asian participants: 21.3% mean weight loss with CagriSema (similar to overall population) Safety profile consistent across ethnicities GI tolerability similar but potentially lower discontinuation rates in Asian populations Clinical Significance: Supports global applicability of cagrilintide-based therapies across diverse populations

Fischberg et al, 2000

Free radicals are unstable molecules generated by normal metabolism, UV radiation, air pollution, alcohol processing, and physical stress

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Control of mitochondrial integrity influences oocyte quality during reproductive aging

Deposition in this region was maximized using nasal powders instead of liquid GHRL formulation [110]