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Management of ARIA may include discontinuation of the medication either temporarily or indefinitely To ensure that ARIA is identified should it occur, the appropriate use recommendations (AUR, i.e., guidelines for clinicians to administer new therapies safely and effectively) for lecanemab suggest health care professionals obtain MRI scans of the brain before the 5th, 7th, 14th and 26th infusions, in addition to a baseline scan before starting treatment

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How to Minimize Injection Site Reactions Patients can take several steps to reduce the chance or severity of injection site reactions: Rotate injection sites Avoid injecting in the same spot repeatedly