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Patients who had larger body mass indexes BMIs greater than 35 lost even more weight, successfully shedding 85 pounds or 30.3% of their body weight after about two years

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The GLP-1 class is the most scientifically credible candidate for disease modification in osteoarthritis to emerge in many years Jay Karri, University of Maryland School of Medicine GLP-1s and addiction How GLP-1s act in the brain is now a huge area of research that could potentially transform addiction treatment

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Its underexploitation in metabolic indications likely reflects disciplinary silos rather than a lack of biological relevance

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