Obesity is a key driver of the most prevalent cardiometabolic diseases, serving as a critical factor in the development of cardiovascular disease, such as ischemic heart disease and stroke [11], and constituting the leading modifiable cause of type 2 diabetes [12]
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Weight loss surgery centers benefit from positioning medications as ineffective
This structural convergence with known efficacious non-peptidic agonists provides additional support for the plausibility of the predicted binding mode and reinforces the relevance of the consensus-driven virtual screening strategy employed in this study
Comparative genomics of chemosensory protein genes reveals rapid evolution and positive selection in ant-specific duplicates
Idiopathic Parkinsons disease, progressive supranuclear palsy and glutathione metabolism in the substantia nigra of patients