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Alcohol Alcohol 18:227237 Soyka M, Morhart-Klute V, Horak M (2002) A combination of carbamazepine/tiapride in outpatient alcohol detoxification-results from an open clinical study

Lipoperoxidation damage of spermatozoa polyunsaturated fatty acids (PUFA): scavenger mechanisms and possible scavenger therapies

When intestinal microecology is disrupted, LPS enters blood circulation, activates the Toll-like receptor 4 (TLR4) signaling, and upregulates the expression of the NF-B pathway, which in turn promotes the differentiation and activity of osteoclasts, leading to severe bone loss and osteoporosis (62)

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In the near future, we are likely to see increasingly sophisticated preclinical models of irAEs, risk stratification with irAE biomarkers, and evidence based approaches for the management of irAE subsets such as steroid-refractory disease (Fig

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