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Prenatal exposure to DDT and DDE increased the risk of obesity during childhood and adulthood, with existing evidence pointing to the sex-specific effects of these compounds [117,118,119,120,121]

In brief, indoleamine 2,3-dioxygenase (IDO) activity is increased during inflammation, leading to increased conversion of tryptophan to kynurenine, reducing substrate availability for serotonin synthesis

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For patients exploring antioxidant support as part of precision wellness, understanding your baseline glutathione status and oxidative stress markers can help guide more targeted supplementation conversations with your healthcare provider

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For individuals with sensitive stomachs, taking tablets with a small amount of water or immediately before a light meal may help prevent any digestive discomfort