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Medications maintain therapeutic drug levels continuously, whereas food-stimulated GLP-1 secretion occurs in pulses after meals and is rapidly degraded

The therapeutic action of omega-3 fatty acids appears to be mediated through the downregulation of pro-inflammatory cytokines, the enhancement in antinociceptive mediators such as resolvins and protectins, and the modulation of the endocannabinoid system

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Some observers have opined that the European agency is stricter than the US Food and Drug Administration, which has not yet addressed this issue

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