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The standard protocol involves increasing the dose every four weeks

Subcutaneous administration achieves 7085% bioavailability compared to 4050% for oral routes due to hepatic first-pass metabolism

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The most commonly reported side effects in clinical trials include: Nausea Vomiting Diarrhea Constipation Most of these symptoms were mild to moderate and tended to improve over time as the body adjusted to the medication, especially when doses were increased gradually

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