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Heres what makes them different: PPIs like omeprazole (Prilosec), esomeprazole (Nexium), and pantoprazole (Protonix) work by: | Treatment | Mechanism | Duration | Effectiveness for GLP-1 Users | Availability | |||-|-|| | Calcium Antacids (Tums, Rolaids) | Neutralizes existing acid | 30-60 minutes | Low-Moderate | OTC | | H2 Blockers (Pepcid, Tagamet) | Reduces acid production | 4-8 hours | Moderate | OTC & Prescription | | PPIs (Prilosec, Omeprazole) | Blocks acid pumps | 24+ hours | High | OTC & Prescription | | Alginates (Gaviscon) | Forms protective barrier | 4 hours | Moderate | OTC | | Combination Approaches | Multiple mechanisms | Varies | High | Varies | Many Klarity Health patients have found success with a proactive approach to managing GLP-1-related heartburn: Some healthcare providers recommend starting a PPI like omeprazole before heartburn symptoms develop, especially if you have a history of acid reflux
Slows the emptying of food from the stomach, which in turn slows digestion and keeps people feeling full longer
Anxiety and Hyper-arousal: By boosting GABA, serotonin, and dopamine, it calms the central nervous system, reducing the constant feeling of being "wired and tired" that plagues ME/CFS patients
Scientific Classification A naturally occurring tripeptide composed of gamma-glutamyl-cysteinyl-glycine
Gastroesophageal Reflux Disease (GERD) Intestinal Dysmotility High blood sugar from diabetes can damage the nerves that coordinate the movements of the intestines, too
Aging, stress, and poor nutrition can deplete it but this formula helps restore balance with 150mg of reduced glutathione in every dose
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