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Timing : Apply at consistent times as directed to maintain steady drug levels

its relatively short half-life requires twice-daily administration [17]

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Therapeutic effects become more pronounced at 4mg and above

The effect is broad reaching and is responsible for 5 million deaths per year from noncommunicable diseases including cardiovascular disease, diabetes, and cancer

In TRIUMPH-4, participants with obesity and knee osteoarthritis didn't just lose weight - they also experienced a 75% reduction in pain scores