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Although our results suggested that the scan at 120-min post-injection and/or repeated scans might have potential benefit on insulinoma detecting in Pdx1-Cre;Trp53 R172H ;Rb f/f mice, further clinical investigations are warranted to confirm the optimal scan protocol for detecting insulinoma using our probe

This increase correlated with a significant reduction in the amount and expression of PVY NTN and the induction of the HR response

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