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Reducing the recruitment of -arrestin and the residence time of the ligand towards the receptor, thus decreasing internalization, is presumably the key of incretin drugs

In methylmalonic acidemia, propionylcarnitine (C3), 2-methylcitrate (MCA), and methylmalonic acid (MMA) are accumulated during propionyl-CoA metabolism

Researchers mix the powder with a sterile solution before testing

It is found in the cytosol, endoplasmic reticulum, vacuoles, mitochondria, chloroplasts, peroxisomes, and the apoplast (Noctor and Foyer 1998)