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One could hypothesize that these endoperoxide drugs accumulate and act on targets that lead to the production of reactive oxygen species, which ultimately affect cytosolic GSH levels

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Most cases are viral or related to reflux, allergies, or smoking, but persistent or worsening symptoms, especially with red flags like breathing difficulty, drooling, neck lumps, or weight loss, require urgent evaluation

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This accumulation instigates oxidative stress, inflammatory responses, and promotes a pro-aging phenotype (Zgutka et al., 2023)