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Warren JW, Brown J, Tracy JK et al: Evidence-based criteria for pain of interstitial cystitis/painful bladder syndrome in women

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Furthermore, some people may experience resistance to certain drugs over time, making it necessary to switch medications, which can be a trial-and-error process

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The sample size was calculated to provide at least 90% power for showing bioequivalence between the 1G and 2G formulations for all three dose groups, based on the standard acceptance limits (0.80001.2500) to ensure sufficient power to confirm bioequivalence in accordance with the EMA, FDA and PMDA guidelines

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