The FDA hasn't reviewed compounded versions for safety, effectiveness, or manufacturing quality as finished drug products
In high L-arginine-dependent tumors, such as breast cancer (Abdelmagid et al., 2011), CRC (Lu et al., 2013), and HCC (Kishikawa et al., 2015), increased expression of the transporter CAT-1 ( SLC7A1 ) has been observed, and CAT-1 ( SLC7A1 ) knockdown decreases the viability of cancer cells and induces apoptosis
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These reactions are generally mild to moderate in severity and self-limiting , requiring no specific treatment beyond standard wound care