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This sounds basic, but mechanical breakdown in the mouth reduces the particle size that reaches the stomach

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Eli Lilly experimental obesity drug Retatrutide hits up to 30% weight loss in pivotal trial Eli Lilly (NYSE:LLY) announced historic topline results from its Phase 3 TRIUMPH-1 clinical trial, showing that its next-generation investigational drug, retatrutide, helped adults with obesity or overweight lose an average of up to 30.3% of their body weight

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