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Medical Guidance: Who Should Consider Duration When Dosing Patients with significant renal impairment, hepatic disease, advanced age, or those taking medications that inhibit GLP-1 metabolism should discuss duration implications with their provider before starting therapy

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Patients with hypocarnitinemia at timepoint 2 showed a significant percent seizure increase while seizures continued to decrease in the normal carnitine group

If you already have delayed gastric emptying, adding a long-acting amylin analog on top of that could create problematic levels of GI stasis

Clinical studies have shown that low levels of IGF-1 are associated with an increased risk of cardiovascular diseases, including coronary heart disease and stroke