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This adaptive response can slow weight loss despite maintained exercise habits

These hormones regulate hunger, eating behavior, glucose metabolism, and adipose tissue

models suggest a nearly 700% increase in youth with type 2 diabetes

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In the Pharmacologic Approaches to Glycemic Treatment: Standards of Care in Diabetes published in 2024, it was recommended to start GLP-1 RA sodium-glucose co-transporter 2 inhibitors (SGLT2i) in patients with T2DM and ASCVD, while also commenting upon noted benefit in specifically HFpEF as well [53]