Individual response and healthcare provider recommendations determine the precise timing between injections, allowing for personalized treatment protocols that optimize results while maintaining safety

TIER PLANS TIER 1 (5mg total) $195 total for 8-10 week supply Monthly cost breakdown: $78-$97 based on weekly dose Recommended if new to treatment or for those on 0.2-0.6mg/week TIER 2 (10mg total) $230 total for 8-10 week supply Monthly cost breakdown: $92-$115 based on weekly dose Recommended for those on 0.7-1.2mg/week TIER 3 (20mg total) $260 total for 8-10 week supply Monthly cost breakdown: $104-$130 based on weekly dose Recommended for those on 1.3mg/week and up TIER 4* (30mg total) $300 total for 8-10 week supply For patients approved to be on high dose therapy of 3-4mg per week Monthly cost breakdown: $120-$150 based on weekly dose TIER 5* (40mg total) $350 total for 8-10 week supply For patients approved to be on high dose therapy of 4-5mg per week Monthly cost breakdown: $140-$175 based on weekly dose Southend Pharmacy - Semaglutide/B6 Injection Up to 90 days BUD

This includes individuals with severe anxiety or other psychological disorders, thyroid dysfunction, cardiovascular disease, and those who are pregnant or breastfeeding
Chapman LE, Darling AL, Brown JE
Research on the MOTS-c analog CB4211 used 25 mg per day (a much higher dose), but native MOTS-c protocols trend lower
doi: 10.1016/s0167-0115(02)00034-4