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Pharmacology: First-line T2D meds: #GLP-1 based drugs (e.g., #Semaglutide), #SGLT2 inhibitors

Zydus will market a 15 mg reusable pen under the brand names Semaglyn, Mashema and Altreme, while Lupin will co-market Zydus injection in India under the brand names Semanext and Lupins Livarise

(PubMed) Eshak ES, Iso H, Yamagishi K, Cui R, Tamakoshi A

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Importantly, when semaglutide is used with insulin or sulfonylureas in patients with diabetes, there is an increased risk of hypoglycemia that may require dose adjustments of these medications

Muscle fibers are protected against oxidative stress by a complex system of endogenous and exogenous antioxidants