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Such trials are necessary to determine whether the promise shown in preclinical research translates to meaningful human benefit and to establish safe, effective dosing protocols

[DOI] [PMC free article] [PubMed] [Google Scholar] [14].Mehdi SF, Pusapati S, Anwar MS, Lohana D, Kumar P, Nandula SA, et al

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Theodorakopoulou E, McCarthy A, Perico V, Aguilera SB

PDE5 inhibitors can help symptoms but may lead to tolerance

A lower but significant reduction in labeling was additionally observed for Go-Nt 7 by the combined depletion of zDHHC5/11, and for MGNC-Nt 7 by zDHHC3/7 (Fig