GLP and GLP-1R play an important role in regulating blood sugar and maintaining energy homeostasis
Side effects often improve during maintenance as your gastrointestinal system fully adjusts
Kopetz S , Lesslie DP, Dallas NA, Park SI, Johnson M, Parikh NU, Kim MP, Abbruzzese JL, Ellis LM, Chandra J, Gallick GE
87 In mice, administering phloretin increased the GLP-1 response and inhibited the GIP response, possibly due to GLUT2 inhibition in K cells
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If side effects persist or significantly impact quality of life, patients should consult their prescribing clinician, who may adjust the dose or timing of administration