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Considering that energy metabolism is also able to regulate ROS levels, we supplemented sodium pyruvate (the sodium salt form of pyruvate, a key energy substrate for cellular metabolism) or JX06 (a compound that modulates pyruvate flux into the tricarboxylic acid cycle) in GGCT-knockdown cells, respectively

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Rabinovich-Nikitin I, Rasouli M, Reitz CJ, Posen I, Margulets V, Dhingra R, et al

Treats hyperpigmentation and skin discolouration