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So to answer your question directly, there are some people who probably don't have that thrifty gene, but just the fact of how their lifestyle is they're not physically active, they're eating a lot of highly processed food and so forth they're gaining weight, but that can change quickly depending upon change in their behavior and in their environment

If the total cholesterol level is high primarily due to a high LDL or triglyceride level, then a cholesterol-lowering program should be considered