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The efficacy of these medications is much greater than anything that has been available up to this point
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[3] Each of these proteins is a zinc-dependent enzyme, binding 3 zinc ions per molecule
--- ## Storage Rules After Reconstitution | Condition | Temperature | Maximum Duration | |-----------|-------------|-----------------| | Refrigerator (ideal) | 3646F (28C) | 28 days from reconstitution | | Room temperature (brief excursion) | Under 77F (25C) | 2 hours maximum | | Frozen | Below 32F | Never discard immediately | **Storage do's:** - Store in the original vial, upright - Keep in the refrigerator door shelf or middle shelf avoid the back where freezing can occur - Protect from light (store in original box or wrap in foil) - Remove from fridge just before drawing your dose
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Weight reduction is an evidence-based therapy for GERD, so the weight loss achieved with GLP-1 medications may actually improve reflux symptoms in many patients, potentially offsetting any direct effects on gastric emptying
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