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Introduction IGF-1 LR3 Overview IGF-1 LR3 (Insulin-like Growth Factor-1 Long Arg) is a synthetic analog of IGF-1 with enhanced stability and potency due to an extended half-life of approximately 2030 hours compared to natural IGF-1s 12-hour half-life

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During ferroptosis, heme oxygenase 1 (Hmox1) is up-regulated with increased free iron release from cardiomyocytes, and then left ventricular remodeling would be triggered, causing severely impaired function of left ventricular in MI patients (Song et al., 2021) (Figure 1)

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