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Human results are not established, and large human trials have not been completed, which is a critical limit to keep in mind

Nutrient sensing, metabolism, and cell growth control

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Nature 532 , 127130 (2016)

Trx1 promotes reverse cholesterol transport (Figure 3) via nuclear translocation of liver X receptor and subsequent increase of ATP-binding cassette transporter A1 expression, thereby inhibiting hepatic steatosis [98] , a disease condition linked to ferroptosis [99]