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The first GLP-RA, twice-daily exenatide, was approved in the USA in 2005 [3] and, most recently, semaglutide received approval for administration by injection in 2017 [4] and in an oral formulation in 2019 [5]

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In addition, increased levels of superoxide dismutase have been reported among schizophrenia patients resistant to medical treatment (Zhang et al