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Recently, in addition to the central maintenance of food intake, GLP-1R signaling has begun to be considered in the context of the regulation of the stress response, as it is indicated that it can activate both the hypothalamicpituitaryadrenal (HPA) axis as well as the sympathetic nervous system [15, 16]

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This guide explains why nerve pain occurs after foot surgery, describes common postoperative sensations, and provides guidance on when ongoing nerve pain should be assessed by a foot and ankle specialist