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Many clients pair B vitamins with amino acids, antioxidants or NAD+ for more comprehensive support

Other patients may be unable to tolerate the side effects of the standard starter dose, but microdosing allows them to begin at an even lower level

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According to one particular study that included 38 adults, taking a beetroot juice supplement increased nitric oxide levels by 21% after just 45 minutes (R)

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No dosage adjustment is recommended for renal or hepatic impairment, though patients should be monitored for dehydration-related acute kidney injury during significant gastrointestinal adverse effects