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In its complete response letter (CRL), the regulator said the application could not be approved based on data submitted to date and requested another Phase III study to further assess the safety and efficacy of the treatment, according to Lykos

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We observe that OVCAR5 has modest to robust expression of all three genes while SKOV3 and CAOV3 each lack robust expression of at least one of the three genes (Fig

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(3) V Susi, G Masirevi, and S Toti (1987) The effects of delta-sleep-inducing peptide (DSIP) on wakefulness and sleep patterns in the cat Brain Research, 1987 Jun 30, Volume 414 (Issue 2), Pages 262-70