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Conclusion: A Glimpse into the Future of Obesity Care The results from ATTAIN-MAINTAIN offer more than just data on a new molecule

Decrease medication dosing (due to enhanced absorption of medication as well as conversion from T4 to T3) Pathogenic and opportunistic bacteria have been shown to bind to thyroid hormones and prevent utilization and absorption Decrease rates of depression, anxiety, brain fog (due to microbiota influences on neurotransmitter creation) Decrease antibodies (due to the immuno-modulating effects of commensal bacteria) Decrease TSH (again, due to the microbiotas impact on neurotransmitter and eventually hypothalamic-pituitary function as well as the improved absorption and conversion of thyroid hormones) Decreased inflammation (from both the direct impact on inflammatory and anti-inflammatory metabolites and the immune-modulating effects of probiotics) Microbiota play a role in developing the GALT (gut associated lymphatic tissue) where approximately 70% of the immune system of the entire body resides

DOI: 10.1093/jat/27.7.520 49

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