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Indeed, using different lung cancer models, we demonstrated that the DDX3X degrader J10 efficiently induces DDX3X degradation and exhibits significantly more anti-tumor effects in all in vivo models with less toxicity compared to RK-33

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Those who are pregnant, have asthma, or upcoming surgery should consult a physician

Several small molecule inhibitors targeting the PDGF/PDGFR pathway have been developed

Samples were split for baseline and GCL activity measurements

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