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Generalized linear models were used to model the associations between time and treatment and the proportion of patients with severe fatigue or significant depression

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The drugmaker completed phase 3 studies for orforglipron, an oral GLP-1 medicine, this year

Additionally, lysosome-associated membrane protein 3 (LAMP3) is elevated within the salivary glands of specific individuals suffering from SS, and the resulting lysosomal dysfunction serves as a crucial factor in the evolution of the disease [280]

Some research suggests these medications may reduce inflammation and improve insulin signaling in the brain, which are mechanisms believed to play a role in neurodegenerative diseases

That difference is what matters here