Our bodies have experienced an insidious decline over the past half-century that has been caused by never-ending consumption of foods that can trigger our brains addictive circuits
Zorn S, Bounds R, Williamson A, et al
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Clinical trials demonstrate significant weight reduction, with patients losing approximately 15% of body weight over 68 weeks with semaglutide (STEP 1 trial) and up to 21% with tirzepatide 15 mg over 72 weeks (SURMOUNT-1 trial)
Comparisons drawn against semaglutide and tirzepatide are cross-trial rather than head-to-head, which limits what can properly be concluded from them
Obesity is one of the most serious health issues facing the nation and is associated with many health conditions, ranging from cardiovascular diseases to cancers, so effective medications to help people control their weight could have substantial health benefits